Science is supposed to cure disease and improve life, but sometimes confidence goes off the rails. Today, we are taking you on a tour through history’s wildest moments when science went completely off the rails, including incidents where confidence reached levels of blowing up a dead whale, dropping cats out of planes, and poisoning an entire generation.

Jennifer Kesse was a 24-year-old woman with a bright future who vanished from her home in Orlando, Florida, in January 2006. She had just returned from a trip and spoke to her family the night before. When she failed to show up for work, her family immediately knew something was wrong.